An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
نویسندگان
چکیده
منابع مشابه
An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
Cells of the innate immune system secrete cytokines early in immune responses that guide maturing T helper (Th) cells along appropriate lineages. This study investigates the role of cytokine networks, bridging the innate and acquired immune systems, in the pathogenesis of an organ specific autoimmune disease. Experimental allergic encephalomyelitis (EAE), a demyelinating disease of the central ...
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1 Author contributions are as follows: SR: conception of the research reported in the paper, flow cytometry, statistical analyses, writing of the manuscript and review of the accuracy of the reported results; GB, AP, AM, ADF, SP, AC, GS, DGdR: Cell cultures, immunocytochemistry, molecular biology, ELISAs SD: Immunoblotting FN, GP, LP: Molecular biology SS, RM, SF: DNA microarray analysis and re...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1998
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.187.4.537